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Mechanism and treatment of Sirtuin family in vascular calcification
1 Introduction Vascular calcification (VC) encompasses a range of conditions characterized by the abnormal deposition of calcium and phosphorus within the vascular wall. It is increasingly acknowledged as an active and regulated process, akin to bone formation (1). The occurrence of VC involves the participation of various cell types, including macrophages, endothelial cells, and vascular smooth muscle cells (VSMCs), which play an essential role in this process (2).
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