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Association of one-carbon metabolism-related nutrients with gestational diabetes mellitus stratified by MTNR1B polymorphisms in Chinese populations
Abstract This study aimed to explore the associations of melatonin receptor 1B (MTNR1B) genetic variants with gestational diabetes mellitus (GDM) and to examine how MTNR1B single-nucleotide polymorphisms (SNPs) might influence the association between one-carbon metabolism (OCM)-related nutrients and GDM. This cross-sectional study analyzed 1,254 pregnant women for three SNPs (rs1387153, rs10830962, and rs10830963) in MTNR1B, as well as serum folate and vitamin B12.
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