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Yinzhu Luo

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Articles

The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants

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By Jelena Marjanovic, Marc Parisien, Benedikt Hindelang, Liu Cao, Yongxia Shi, Tiaozhen Zhu, Siyao Huang, Yanxi Ji, Yinzhu Luo, Hemi Luan
| Science Magazine Verified
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus driving the ongoing coronavirus disease 2019 (COVID-19) pandemic, continues to rapidly evolve. Due to the limited efficacy of vaccination in prevention of SARS-CoV-2 transmission and continuous emergence of variants of concern (VOC), orally bioavailable and broadly efficacious antiviral drugs are urgently needed.
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