Yiyan Yin

Mimicking NADPH Oxidase and Lipoxygenase by Biodegradable Single-site Catalyst via Cascade Reaction to Trigger Tumor-Specific Ferroptosis Ferroptosis exhibits promising potential in cancer therapy via lipid peroxidation (LPO) accumulation, while its therapeutic efficacy is normally limited by inadequate ROS production and adverse effects on normal tissues.

Revealing Axial-Ligand-Induced Switching of Spin States for Controllable Single Electron Transfer-based Radical Initiation Radicals are highly reactive for coupling reactions while the applications are normally limited by the uncontrollable initiation and chaotic conversions.

Glass electrospray for in situ detection of living cells by mass spectrometry Here, we developed a platform of glass electrospray coupled with mass spectrometry (MS) to detect living cells cultured on glass slides. With a high electric voltage, the adherent cells were detached from the glass surface and then migrated to the tip of the glass slide. In this way, the intact cells can be well detected without dilution, matrix affection, adsorption, contamination, or damage.