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Yiying Guo on Muck Rack

Yiying Guo

As seen in: Lung Cancer
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Articles

Whole-exome sequencing of rectal neuroendocrine tumors

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By Yuanliang Li, Yiying Guo, Zixuan Cheng, Chao Tian
| bioscientifica.com
Abstract The genetic characteristics of rectal neuroendocrine tumors (R-NETs) were poorly understood. Depicting the genetic characteristics may provide a biological basis for prognosis prediction and novel treatment development. Tissues of 18 R-NET patients were analyzed using whole-exome sequencing. The median tumor mutation burden (TMB) and microsatellite instability (MSI) were 1.15 Muts/MB (range, 0.03–23.28) and 0.36 (range, 0.00–10.97), respectively.
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Molecular and functional heterogeneity of primary pancreatic neuroendocrine tumors and the metastases

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By Yiying Guo, Chao Tian, Zixuan Cheng, Ruao Chen
| ncbi.nlm.nih.gov
Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software
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YAP1 protein expression has variant prognostic significance in small cell lung cancer (SCLC) stratified by histological subtypes

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By Byers L.A, Xin Wang, Yiying Guo
| Lung Cancer Verified
Highlights • The positive rate of YAP1 protein expression was significantly higher in C-SCLC than P-SCLC. • Positive expression of YAP1 was associated worse OS exclusively in C-SCLC, but for P-SCLC, YAP1 expression was not prognostic. • The small cell components of P-SCLC and C-SCLC were of different entities with variant YAP1 expression and different prognostic vulnerability which further implicated potential different targetable oncogenic pathway between C-SCLC and P-SCLC.
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