Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Yong-Joon Cho
Igidamycins A-C, Rare Sugar-Bearing Anthracycline Glycosides from a Marine Actinomycete, Streptomyces sp. | Organic Letters
Abstract Click to copy section linkSection link copied! Genome-guided mining of marine Streptomyces sp. GCU-142 led to the identification of three unprecedented sugar-bearing anthracycline glycosides, igidamycins A–C (1–3). The structures of 1–3 were assigned by spectroscopic analysis including NMR, HR-MS, and UV spectroscopy. Their configurations were determined by ROESY NMR data, the modified Mosher’s method, l-cysteine methyl ester derivatization, and TD-DFT ECD calculations.
NFAT5 dictates crosstalk between intestinal epithelial regenerative capacity and microbiota in murine colitis models
ResearchGastroenterologyImmunology Open Access | 10.1172/JCI183093 J Clin Invest. https://doi.org/10.1172/JCI183093. Copyright © 2025, Park et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Hypertonic and hyperosmolar stimuli frequently pose challenges to the intestinal tract.
Elongation factor P controls ribosomal frameshift of a Salmonella antimicrobial resistance gene
Abstract Ribosomes translate mRNAs by matching every 3-nucleotide sequence in mRNA, producing the corresponding proteins. As the amino acid sequence directly dictates the activity of the protein, frameshifts often lead to unexpected effects. Here, ribosome profiling reveals that the intracellular pathogen Salmonella Typhimurium suppresses frameshift in the ugtL antimicrobial resistance gene during translation.
A HigB-like toxin promotes non-replicating Salmonella inside macrophages by inhibiting ribonuclease III
Abstract Many bacteria are often resistant to antibiotic treatment because they can slow down their growth rate, thereby attenuating the drug's effectiveness. A similar growth-rate control is observed in pathogens that infect and persist inside their hosts. The bacterial toxin-antitoxin (TA) system serves as a non-heritable phenotypic switch by slowing down growth through the expression of a toxin component.
Live Malassezia strains isolated from the mucosa of patients with ulcerative colitis
Abstract The human gut is inhabited by a complex ecosystem of diverse microorganisms. While most studies on the gut microbiota have focused on bacteria, accumulating evidence has underscored the role of the mycobiota in inflammatory bowel disease (IBD). This study is the first to isolate and characterize live Malassezia globosa strains from the intestinal mucosa of patients with ulcerative colitis. Malassezia species primarily inhabit the human skin. We therefore compared the M.
Mycobacterium potentiates protection from colorectal cancer by gut microbial alterations
ABSTRACT Not only are many Mycobacteria pathogens, but they can act as strong nonspecific immunopotentiators, generating beneficial effects on the pathogenesis of some diseases. However, there has been no direct evidence of the effect of mycobacterial species on colorectal cancer (CRC). Herein, we showed that there may be a meaningful inverse correlation between the incidence of tuberculosis and CRC based on global statistics and that heat-killed M. tuberculosis and live M.
A Novel Virus Alters Gene Expression and Vacuolar Morphology in Malassezia Cells and Induces a TLR3-Mediated Inflammatory Immune Response
Research Article | Host-Microbe Biology Minji Park, Yong-Joon Cho, Donggyu Kim, Chul-Su Yang, Shi Mun Lee, Thomas L. Dawson Jr., Satoshi Nakamizo, Kenji Kabashima, Yang Won Lee, Won Hee Jung Floyd L. Wormley Jr., Editor DOI: 10.1128/mBio.01521-20 ABSTRACT Most fungal viruses have been identified in plant pathogens, whereas the presence of viral particles in human-pathogenic fungi is less well studied.
A Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for Capsule Formation in Cryptococcus neoformans
Eunsoo Do, Yong-Joon Cho, Donghyeun Kim, James W. Kronstad and Won Hee Jung Genetics August 1, 2020 vol. 215 no. 4 1171-1189; https://doi.org/10.1534/genetics.120.303270 Abstract Iron is essential for the growth of the human fungal pathogen Cryptococcus neoformans within the vertebrate host, and iron sensing contributes to the elaboration of key virulence factors, including the formation of the polysaccharide capsule. C.
A Vanillin Derivative Causes Mitochondrial Dysfunction and Triggers Oxidative Stress in Cryptococcus neoformans
Vanillin is a well-known food and cosmetic additive and has antioxidant and antimutagenic properties. It has also been suggested to have antifungal activity against major human pathogenic fungi, although it is not very effective. In this study, the antifungal activities of vanillin and 33 vanillin derivatives against the human fungal pathogen Cryptococcus neoformans, the main pathogen of cryptococcal meningitis in immunocompromised patients, were investigated.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Yong-Joon
Contact Yong-Joon, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack