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Yongchuan Li

As seen in: Wiley Online Library, MDPI
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Articles

SUR1‐TRPM4 Regulates Aquaporin‐4 Subcellular Localization by Astrocytic Endfeet Calcium Signals Following Status Epilepticus

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By TingTing Yang, Zhenzhou Lin, Mingjia Yu, Yongchuan Li
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description glia70056-sup-0001-Figures.docxWord 2007 document , 3.1 MB Figure S1. Flow diagram and electroencephalographic patterns. (A) Flow diagram for the study assessments on a timeline. (B) Representative EEG traces. Figure S2. TTX do not affect astrocytic Ca2+ signals following SE.
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Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

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By Yongchuan Li, Haiping Zhou, Jiaxin Xie, Mingjia Yu
| Wiley Online Library Verified
1 INTRODUCTION Stroke is the second leading cause of mortality globally and the primary contributor to long-term disability [1]. Ischemic stroke accounts for the majority of cases (86.8%) [2]. Cerebral edema typically develops within 6–12 h following the onset of cerebral ischemia, peaking at 48 h [3]. It is characterized by fluid accumulation within brain tissue, resulting in secondary neurological deterioration and irreversible neuronal damage.
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