Youlu Chen

ROS responsive EPO nanoparticle ameliorates ionizing radiation-induced hematopoietic injury Huiyang Li, Xiaoyu Liang, Jianwei Duan, Youlu Chen, Xinxin Tian, Jinhan Wang, Hailing Zhang, Qiang Liu and Jing Yang Abstract Stimulus-responsive polymer materials have attracted much attention as drug carrier because of the ability to deliver drug to the active site. Reactive oxygen species (ROS) plays crucial roles in cellular signaling and regulation of oxygen homeostasis.

Currently, development of subunit vaccine based on recombinant antigens or peptides has gradually become an important alternative option for traditional vaccine. However, induction of potent immune response with desired efficacy remains a major challenge. The nanoparticle-based antigen delivery system has been considered a potential carrier system to improve the efficacy of subunit vaccine.