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Young Lee

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Articles

Adjuvant radiotherapy and skin cancer risk in breast cancer survivors: a nationwide cohort study in Korea

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By Dooreh Kim, Hye Sun Lee, Soyoung Jeon, Jin Lee, Young Lee, Soo Youn Bae, Woo-Chan Park, Jin Song, Chang Ik Yoon, Je Hyun Chin
| Nature Verified
Abstract Adjuvant radiotherapy (RT) is standard for breast cancer, but its impact on skin cancer risk, especially in Asian populations, remains unclear despite advanced techniques. This study aimed to assess skin cancer incidence following RT in a large South Korean cohort.
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DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancer

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By Wanpei Cai, Sebastian Pohl, Xianning Lai, Vivien Koh, Haoran Ma, Mark Agostino, Amudha Deivasigamani, Yi Yuan, Tuan Zea Tan, Jianxiang Chen, San Hue Hua, Shiyuan Guo, Janet Teng, Jas Min Chin, Young Lee, Madhu Kanchi, Karthik Ramesh, Yu Keung Mok, Ruby Yun-Ju Huang, Jayantha Gunaratne, Melissa Jane Fullwood, George Yip, Gautam Sethi, Jeremy P. Blaydes, Kam Man Hui, Jit Kong Cheong, Nicholas S. Tolwinski, Wei Peng Yong, Patrick Tan, Kevin Myant, Alan Prem Kumar, Catharine Shi-Yun Low, Nawat Bunnag, Jahnavi Suresh, Muthukumar Rajasekaran, Celestial T. Yap, Peter Edward Lobie, Venetia Jing-Tong Kok, Arunasalam Dharmarajan, Deog Joong Kim
| Nature Verified
Abstract Triple-negative breast cancer (TNBC) is a clinically aggressive subtype lacking targeted therapies, often characterized by hyperactivation of the Wnt/β-catenin signaling pathway and an enriched population of cancer stem cells (CSCs). Here, we identify the DEAD-box RNA helicase DP103 as a novel modulator of Wnt/β-catenin signaling in TNBC, acting independently of its canonical helicase function.
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Impact of Commercial Polyolefin Architecture and Composition on Its Ability to Compatibilize High-Density Polyethylene/Isotactic Polypropylene Blends

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By Young Lee, Kook Choong Kim, Han Mo Jeong
| Wiley Online Library Verified
1 Introduction The accumulation of plastics in the world poses a significant problem as landfills continue to fill and plastic production shows no signs of slowing down [1-3]. In 2017, the global annual production of plastics was estimated to be 438 metric tons (Mt) and is expected to reach 1.1 billion Mt by 2050 [1]. This is in large part due to plastic being used once and then discarded, which became prevalent as plastics are cheap to produce and market.
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