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Yu-Chia Chen on Muck Rack

Yu-Chia Chen

As seen in: Nature, Wiley Online Library, Frontiers, MDPI, ACS Publications, BMC Genomics, BioRxiv, Dove Medical Press, JNeurosci, eLife and
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Articles

RoboA reinforces planarian stem cell fate through FoxA and Anosmin1a - Nature Communications

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By Fu-Yu Tsai, Yu-Chia Chen, Engin Ozkan, Indya E. Weathers
| Nature Verified
Abstract Whole-body regeneration requires adult stem cells with high plasticity to differentiate into missing cell types. Planarians possess a unique configuration of organs embedded in a vast pool of pluripotent stem cells. How stem cells integrate positional information with discrete fates remains unknown. Here, we use the planarian pharynx to define the cell fates that depend on the pioneer transcription factor FoxA.
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Large Spin‐Orbit Torque with Multi‐Directional Spin Components in Ni4W (Adv. Mater. 32/2025)

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By Yifei Yang, Seungjun Lee, Yu-Chia Chen, Qi Jia
| Wiley Online Library Verified
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Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells

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By Yu-Chia Chen, Mamoru Takada, Aerica Nagornyuk, Muhan Yu
| eLife
eLife Assessment This study provides valuable findings that MK2 inhibitor CMPD1 can inhibit the growth, migration and invasion of breast cancer cells both in vitro and in vivo. The evidence supporting the claims of the authors is solid, although the detailed molecular mechanism and additional animal experiments would strengthen the paper. This study will be of interest to the breast cancer field.
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