Yu-Ying Li
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Bortezomib exhibited bacteriostatic activity and pro-inflammatory effect against Mycoplasma pneumoniae
Abstract Mycoplasma pneumoniae (MP) is an important respiratory pathogen. Growth inhibition and regulation of inflammation in lung are key to the treatment of MP infections. Bortezomib, a proteinase inhibitor, was found to possess both functions in this study. Firstly, bortezomib showed dose-dependent bacteriostatic activity against MP in culture medium. Decreases in glucose catabolism (changes of pH) and colony-forming units (CFUs) were detected at 3 d post-incubation (bortezomib>10 nM).
PoARF19 interacts with PoYUC10 and PoGA2ox2 to modulate auxin and gibberellin levels to promote lateral roots development in tree peony
CONFLICT OF INTEREST The authors have no conflict of interest to declare. DATA AVAILABILITY STATEMENT All data supporting this study are available upon reasonable request. The RNA-seq data that support the findings of this study have been submitted to the National Centre for Biotechnology Information (NCBI) (SRA, PRJNA1222577). The datasets supporting the results in this study are included within the article and its supporting information (Figures –S10; Tables ).
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