Yuanzhong Yang on Muck Rack

Yuanzhong Yang

As seen in: Nature, MDPI, Cell Reports Medicine
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Articles

Author Correction: A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities

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By Zhenyu Yang, Shiyou Wei, Hao Duan, Xiuqi Wang, Dainan Zhang, Yulan Deng, Yuanzhong Yang, Yin Ku, Wanming Hu, Chaowei Zou, Meiqin Tang, Yu Jiang, Yu Chi Liu, Hongbin Lan, Zexin Chen, Gilberto Ka-Kit Leung, Wang Jia, Yonggao Mou, Lunxu Liu, Gao Zhang
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-026-68748-y, published online 26 January 2026 In the Acknowledgements section of this article the grant number relating to Science and Technology Support Program of Sichuan Province given for Shiyou Wei was incorrectly given as “2023YFS0126 and 2023NSFSC0732” and should have been “2023YFS0126”. The original article has been corrected.
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A longitudinal, multi-omic atlas reveals the emergence of a spatially organized immunosuppressive ecosystem in resistant melanoma

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By Shiyou Wei, Yulan Deng, Jinho Lee, Hongbin Lan, Zhenyu Yang, Marilyne Labrie, Courtney B. Betts, Hao Duan, Benjamin Tate, Joanna Pucilowska, Dennie T. Frederick, Aleigha Lawless, Tatyana Sharova, Yuanzhong Yang, Wanming Hu, Georgia Beasley, Lynn M. Schuchter, Xiuqi Wang, Wei Xu, Megan Vandenberg, Drew Torigian, Shamilene Sivagnanam, Kuang Du, Eric Sugarman, Suzanne McGettigan, Cathy Zheng, Rami N. Al-Rohil, Michael Datto, Giselle Y. López, Smita Nair, David Ashley, Xiaowei Xu, Ravi K. Amaravadi, Giorgos C. Karakousis, Donald M O'Rourke, Steven Brem, Bert W O'Malley, Gokhan Demirkan, Shuangxing Yu, Yiling Lu, Todd Camp, Janice Patterson, Zhi Wei, Christopher L. Corless, Dmitry I Gabrilovich, Yonggao Mou, Keith T Flaherty, Lisa M. Coussens, Genevieve M. Boland, Meenhard Herlyn, Gordon Mills, Lunxu Liu, Gao Zhang, Maria A. Selim
| Cell Reports Medicine Verified
Keywords melanoma immune checkpoint blockade resistance dynamic evolution Introduction In 2022, there were approximately 330,000 newly diagnosed primary cutaneous melanoma cases and 58,645 deaths related to melanoma worldwide.1 Over the past decade, systemic therapies have significantly improved outcomes for advanced or metastatic melanoma.
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A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities - Nature Communications

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By Zhenyu Yang, Shiyou Wei, Hao Duan, Xiuqi Wang, Dainan Zhang, Yulan Deng, Yuanzhong Yang, Wanming Hu, Meiqin Tang, Yu Jiang, Yu Chi Liu, Hongbin Lan, Zexin Chen, Gilberto Ka-Kit Leung, Wang Jia, Yonggao Mou, Lunxu Liu, Yin Ku, Chaowei Zou
| Nature Verified
Abstract The molecular heterogeneity of brain metastases hampers therapeutic development for cures. To address this unmet and urgent need, we construct a comprehensive multi-omic, single cell, and spatially resolved atlas of 1,032 pan-cancer brain metastases, identifying four robust molecular subtypes with distinct biological programs and clinical associations.
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