Yuito Kobori

Submitted: 26 November 2025 You are already at the latest version Pestasulfamides A and B are phenylbenzene-sulfonamides with an eight-membered dilactam, produced by mangrove endophytic fungus Pestalotiopsis sp. HNY36-1D. Herin, the first total synthesis of pestasulfamides A and B was achieved through one-pot protocol. The key step features an iminoketene dimeriazation of anthranilic acid triggered by a sulfonylation in a pyridine/THF system.

Indoline Hemiaminals: A Platform for Accessing Anthranilic Acid Derivatives through Oxidative Deformylation 2-Aminobenzoyl chlorides possess both the nucleophilic nitrogen atom and electrophilic carbonyl group, and thus selective acylation of nucleophile is challenging: Self-dimerization and sluggish reaction occurs.