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Yuki Aibara

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Articles

Imaging–Pathology Discordance During Neoadjuvant Chemotherapy for Pediatric Osteosarcoma

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By Jumpei Ito, Risako Narukama, Yuki Aibara
| Wiley Online Library Verified
Assessment of response to neoadjuvant chemotherapy in pediatric osteosarcoma remains challenging. While histologic tumor necrosis is a well-established prognostic factor, early radiologic evaluation using conventional magnetic resonance imaging (MRI) does not always accurately reflect therapeutic efficacy [1, 2]. Apparent tumor enlargement or increased enhancement on MRI may be misinterpreted as disease progression, which can heavily influence surgical decision-making.
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