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Yulian Yin on Muck Rack

Yulian Yin

As seen in: Taylor & Francis Online, Journal of Medical Case Reports
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Articles

Gasdermin D Inhibition Attenuates Mitochondrial Damage and Cardiomyocyte Pyroptosis in Heart Failure with Preserved Ejection Fraction

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By Linlin Chen, Zhiming Jiang, Yulian Yin
| Taylor & Francis Online
Abstract Heart failure with preserved ejection fraction (HFpEF) represents the most prevalent subtype of heart failure globally, with its underlying pathogenesis remaining incompletely elucidated. Pyroptosis and mitochondrial dysfunction have been implicated in HFpEF progression. In addition, gasdermin D (GSDMD) has been shown to mediate both mitochondrial dysfunction and pyroptosis, yet the specific regulatory mechanisms involved in HFpEF remain to be elucidated.
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