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Yun-Jong Park on Muck Rack

Yun-Jong Park

As seen in: BioRxiv
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Articles

Functional Activity and Binding Specificity of small Ankyrin Repeat Proteins called Ankyrons against SARS-CoV-2 variants.

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By Yun-Jong Park, Nicholas Hurst, Jeremy Fry
| BioRxiv
Abstract Effective management of COVID-19 requires clinical tools to treat the disease in addition to preventive vaccines. Several recombinant mAbs and their cocktails have been developed to treat COVID-19 but these have limitations. Here, we evaluate small ankyrin repeat proteins called Ankyrons that were generated to bind with high affinity to the SARS-CoV-2 virus. Ankyrons are ankyrin repeat proteins comprised of repetitions a structural module.
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Functional Activity and Binding Specificity of small Ankyron Repeat Proteins against SARS-CoV-2 variants

|
By Nicholas Hurst, Jeremy Fry, Yun-Jong Park
| BioRxiv
Abstract Effective management of COVID-19 requires clinical tools to treat the disease in addition to preventive vaccines. Several recombinant mAbs and their cocktails have been developed to treat COVID-19 but these have limitations. Here, we evaluate Ankyrons that were generated to bind with high affinity to the SARS-CoV-2 virus. Ankyrons are ankyrin repeat proteins comprised of repetitions a structural module. Each module consists of a beta-turn followed by two antiparallel alpha-helices.
Open in Who Shared Issue with article?
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