Yun Sung Eom on Muck Rack

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Articles

Tissue inhibitor of metalloproteinases 1 enhances rod survival in the rd1 mouse retina

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By Hwa Sun Kim, Andrew Stehney Vargas, Yun Sung Eom
| PLOS
Retinitis pigmentosa (RP), an inherited retinal degenerative disease, is characterized by a progressive loss of rod photoreceptors followed by loss of cone photoreceptors.
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Reshaping the Cone-Mosaic in a Rat Model of Retinitis Pigmentosa: Modulatory Role of ZO-1 Expression in DL-Alpha-Aminoadipic Acid Reshaping

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By Los Angeles, Yun Sung Eom, Jung-A Shin
| PLOS
In S334ter-line-3 rat model of Retinitis Pigmentosa (RP), rod cell death induces the rearrangement of cones into mosaics of rings while the fibrotic processes of Müller cells remodel to fill the center of the rings. In contrast, previous work established that DL-alpha-aminoadipic-acid (AAA), a compound that transiently blocks Müller cell metabolism, abolishes these highly structured cone rings.
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