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Yun Yu

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Articles

Joint effect of uncertainty-of-outcome and calorie content on food preference - Scientific Reports

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By Lei Zheng, Yinqiang Yu, Pengfei Cheng, Shucheng Cao, Yun Yu, Zhen Yuan, Xueli Chen, Charles Spence
| Nature Verified
Abstract In today’s market, mystery boxes (where the contents are uncertain) introduce uncertainty concerning the outcome, offering the consumer the chance to receive one of several possible foods. However, the role of uncertainty-of-outcome induced in food preference is unclear. This research investigated how uncertainty-of-outcome affects food preference for high- versus low-calorie food products, and its cognitive and neural mechanisms.
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A marginalized three-part interrupted time series regression model for proportional data

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By Shangyuan Ye, Maricela Cruz, Maricela De La Cruz Verified, Ziyou Wang, Yun Yu
| Taylor & Francis Online
Interrupted time series (ITS) is often used to evaluate the effectiveness of a health policy intervention that accounts for the temporal dependence of outcomes. When the outcome of interest is a percentage or percentile, the data can be highly skewed, bounded in , and have many zeros or ones. A three-part Beta regression model is commonly used to separate zeros, ones, and positive values explicitly by three submodels.
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Potential beneficial effects of PD-1/PD-L1 blockade in Alzheimer’s disease: a systematic review and meta-analysis of preclinical and clinical studies - Molecular Psychiatry

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By Yun Yu
| Nature Verified
Abstract Programmed cell death protein 1 (PD-1) and its ligand (PD-L1) are crucial in cancer immune evasion and in modulating neuroinflammation. Although PD-1/PD-L1 signaling is believed to modulate immune and neuronal responses, its role in AD pathophysiology remains unclear, with existing studies reporting inconsistent findings. This systematic review and meta-analysis investigated the effects of PD-1/PD-L1 blockade on AD-related pathology and cognitive behavior in preclinical studies.
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