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Yusmaris Cariaco on Muck Rack

Yusmaris Cariaco

As seen in: BioRxiv
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Articles

NAD+ depletion and altered mitochondrial function are key to the establishment of placental dysfunction in an inflammatory-driven subclass of preeclampsia

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By Shannon Bainbridge, Keir Menzies, Fahmida Jahan, Yusmaris Cariaco
| BioRxiv
Abstract Preeclampsia (PE) is a pregnancy associated hypertensive disease. It is one of the major causes of pregnancy-related maternal/perinatal adverse health outcomes, with a lack of highly effective preventative strategies and/or therapeutic interventions. Our group has previously identified distinct subclasses of pathophysiology underlying a PE diagnosis, one of which exhibits heightened immune activation at the gestational parent-fetal interface, identified as inflammatory-driven PE.
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