Yusuf Ceyhun Erdogan on Muck Rack

Yusuf Ceyhun Erdogan

As seen in: BioRxiv
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Visualizing interactions of VDAC1 in live cells using a tetracysteine tag

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By Johannes Pilic, Benjamin Gottschalk, Furkan E. Oflaz, Yusuf Ceyhun Erdogan
| BioRxiv
Abstract The voltage-dependent anion channel 1 (VDAC1) is a crucial gatekeeper in the outer mitochondrial membrane, controlling metabolic and energy homeostasis. The available methodological approaches fell short of accurate visualization of VDAC1 in living cells. To permit precise VDAC1 imaging, we used the tetracysteine (TC)-tag approach and visualized VDAC1 dynamics in living cells. TC-tagged VDAC1 had a cluster-like distribution on mitochondria.
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