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Yutthana Pengjam

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Articles

Skipjack tuna bone derived biocalcium ameliorates C2C12 myotube atrophy through microRNA29b regulation - Scientific Reports

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By Sompot Jantarawong, Theeraphol Senphan, Yuya Yamaguchi, Kazuya Hasegawa, Yutthana Pengjam, Chanokwanan Youngruk, Nicha Thongchai, Papitchaya Watcharanurak, Pasjan Satrimafitrah
| Nature Verified
Abstract We investigated the protective effects of skipjack tuna (Katsuwonus pelamis) bone-derived biocalcium (Bio) against dexamethasone-induced atrophy in C2C12 myotubes. Bio rescued atrophic morphology, increasing myotube diameter dose-dependently. It mitigated inflammation by suppressing nitric oxide production and the expression and concentration of proinflammatory cytokines (IL-6, TNF-α, IL-1β) significantly and dose-dependently.
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