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Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression
1 Introduction Although the central nervous system (CNS) has long been considered an immune-privileged site [1], innate and adaptive immune cells within the meninges actively monitor and respond to pathological conditions [2].
Copper-doped PDA nanoparticles with self-enhanced ROS generation for boosting photothermal/chemodynamic combination therapy
Copper-doped PDA nanoparticles with self-enhanced ROS generation for boosting photothermal/chemodynamic combination therapy† Chemodynamic therapy (CDT) kills tumor cells by converting intracellular hydrogen peroxide (H2O2) into cytotoxic hydroxyl radicals (˙OH) using metal ion-based agents via Fenton/Fenton-like reactions, exhibiting cancer specificity, excellent safety, and minimal side effects.
Nanozyme mediated high entropy-driven photothermal enhanced tumor catalytic therapy
Nanozyme mediated high entropy-driven photothermal enhanced tumor catalytic therapy Nanozymes mediated catalytic therapy has emerged as a promising strategy for antitumor treatment but it remains imperative to further improve the catalytic efficiency of nanozymes for a potentiated antitumor efficacy.
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