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Yuying Zhang on Muck Rack

Yuying Zhang

As seen in: Color Research & Application, Nature, Wiley Online Library, PLOS Medicine, PLOS ONE, Frontiers, MDPI, Omega, ACS Publications, Globalization and Health and
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Articles

ProSci-246 with dietary guidance alters gut microbiota and metabolism in childhood obesity: a randomized trial

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By Xuan Shi, Weiwei Hu, Cuicui Ma, Lili Yang, Fengnan Lian, Yuying Zhang, Teng Ma, Lai-Yu Kwok, Ruifang Guo, Zhihong Sun, Heping Zhang
| Nature Verified
Abstract Childhood obesity remains a pressing global health challenge with few effective therapeutic strategies. This study combined a cross-sectional analysis of 99 children (49 obese, 50 healthy) with a 3-month, randomized, double-blind, placebo-controlled trial in 95 children with obesity to investigate the role of gut microbiota in pediatric obesity and evaluate Bifidobacterium animalis subsp. lactis ProSci-246 as a microbiota-targeted intervention.
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An endometrial immune atlas across the female menstrual cycle reveals lymphoid aggregates compromise pregnancy

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By Lingtao Yang, JING YANG, Yuye Li, Yiyi Su, Huan Ma, Songchen Cai, Meilan Mo, Lijun Ding, Chunyu Huang, Fenghua Liu, Aiping Qin, Alexandra P. Bielfeld, Udo R Markert, Shuyi Yu, Linlin Wang, Ruochun Lian, Fu Hang, Wenjuan Liu, Elizabeth Soczewski, Astrid Schmidt, Dunja M. Baston-Buest, Nengming Xiao, Kairui Mao, Hao Wang, Xiaoyan Chen, Zhenwei Lan, Yuying Zhang, Tailang Yin, Wanze Chen, Xiaoshan Shi, Shuangyin Wang, Fan Yang, Haixiang Sun, Yong Zeng, Qiyuan Li, Lianghui Diao, Hanjie Li, Jana Pastuschek
| Nature Verified
Abstract The human endometrial immune landscape is critical for homeostasis and pregnancy success, yet its dynamic remodeling across the menstrual cycle and in pathology remains poorly characterized. Here, we construct a comprehensive immune cell atlas of the human endometrium, profiling 53 healthy women and 34 chronic endometritis (CE) patients across precisely staged menstrual cycle phases.
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Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss

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By Ümmügülsüm Yıldız-Altay, Rutha Adhanom, Warda Abdi, Andrew Romasco, Nuha Salam, Robert Li, Haya Raef, Yuying Zhang, Elise Santacruz, Saeed Shakiba, Mridushi Daga, Qi Tang, Thomas Cicuto, Floriane Bretheau, Ann Marshak-Rothstein, Michael Rosenblum, Christina E Baer, Allison M. Keeler, Helen Bui, Amanda J. Martinot, Ramón Almela Verified, Angel S. Byrd, Cheri N. Frey, Jillian M. Richmond, Lauren You, Katelin Murphy, Matthew Olivera, Motahareh Arjomandnejad, Babak Shokrani
| Nature Verified
Abstract Cutaneous lupus erythematosus (CLE) encompasses several autoimmune entities characterized by a T cell-rich infiltrate and alopecia. Here, we perform spatial transcriptomics across three mammalian species to characterize potential T cell-hair follicle communication pathways in the microanatomical niche. In mice, adoptive transfer of either autoreactive CD4 + /OT2 or CD8 + /OT1 T results in skin disease with 35% gene expression overlap.
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