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Articles by Z. C. Su
Sc(OTf)3-catalyzed alkyne-carbonyl metathesis-initiated cyclization for accessing naphtho[2,1-b]furan-1-ones under microwave heating
For reviews: (a) A. H. Hoveyda, A. R. Zhugralin, Nature 450 (2007) 243−251; (b) R. R. Schrock, Angew. Chem., Int. Ed.... Z. Su et al. J. Org. Chem. (2022) M. Curini et al. Synlett (2003) S. Basu et al. Eur. J. Org. Chem. (2018) B. Liu et al. Org. Lett. (2018) A. Saito et al. Org. Lett. (2008) J.U. Rhee et al. Org. Lett. (2005) Y. Sun et al. J. Org. Chem. (2018) C. Ao et al. J. Org. Chem. (2019) B. Chakrabortya et al. Org. Biomol. Chem. (2021) C. González-Rodríguez et al. Org. Lett. (2009) T. Jin et al. Chem. Commun. (2009) L. Liu et al. Beilstein J.
Preparation of trastuzumab-DM1 conjugate with a high drug-to-antibody ratio for breast cancer therapy
Antibody-drug conjugates (ADCs) represent a rapidly developing class of drugs that offer high efficacy in treating cancer, consisting of tumor antigen-specific monoclonal antibodies, linkers, and cytotoxic payloads [1], [2], [3]. By combining monoclonal antibodies and chemotherapeutic drugs through linkers, ADCs can deliver highly toxic payloads selectively to cancer cells while minimizing damage to normal cells [4], [5], [6].
Histone methyltransferase Smyd2 drives vascular aging by its enhancer-dependent activity.
Aging (Albany NY), Dec 2022 This is a preview of a remote PDF: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876634/pdf/ Z. Su, H. Su, J. Xu, G. Wei, L. Qu, T. Ni, D. Yang, Y. Zhu. , Aging (Albany NY), 2022, pp. 70, Volume 15, Issue 1, DOI: 10.18632/aging.204449
The hypothesis was that MRI combined with 18F-FDG PET could detect early response to IRE of liver tumor in a rat liver tumor model.
Big Data, Predictive Analytics, and QI in Kidney Transplant
close Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Log out Cancel In This Article Abstract and Introduction Abstract We sought proof of concept of a Big Data Solution incorporating longitudinal structured and unstructured patient-level data from electronic health records (EHR) to predict graft loss (GL) and mortality.
Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise
2. Material and methods Age (12–18 weeks) and bodyweight (25–30 g) matched male POMC-hrGFP::LepR-cre::tdtomato (PLT) and male NPY-hrGFP::LepR-cre::tdtomato (NLT) mice were used for all whole cell patch-clamp recordings. These mice allow us to identify POMC or NPY neurons that either do or do not express LepR. C57/B6 mice were used for food intake studies. All mice were housed under standard laboratory conditions (12 h on/off; lights on at 7:00 a.m.) and temperature-controlled environment (22–24 °C).
Hypothalamic endoplasmic reticulum stress as a key mediator of obesity‐induced leptin resistance
Obesity is an epidemic disease that is increasing worldwide and is a major risk factor for many metabolic diseases. However, effective agents for the prevention or treatment of obesity remain limited. Therefore, it is urgent to clarify the pathophysiological mechanisms underlying the development and progression of obesity and exploit potential agents to cure and prevent this disease.
Hypothalamic endoplasmic reticulum stress as a key mediator of obesity-induced leptin resistance
Obesity is an epidemic disease that is increasing worldwide and is a major risk factor for many metabolic diseases. However, effective agents for the prevention or treatment of obesity remain limited. Therefore, it is urgent to clarify the pathophysiological mechanisms underlying the development and progression of obesity and exploit potential agents to cure and prevent this disease.
Boosting up phonon-induced luminescence in red fluoride phosphors via composition variation driven structural transformations
In this study, a series of (KxNa1-x)2SiF6:Mn4+ red phosphors with systematic composition variations of alkali metals were synthesized via a low-temperature full-solution approach. Driven by the composition variation, a sequence of continuous structural phase transformations, i.e., from trigonal to mixed, then to orthorhombic, and eventually to cubic phase, is evidently observed in this series of red phosphors.
Triplet harvesting in luminescent Cu(I) complexes by thermally activated luminescence mechanism transition: Impact of molecular structure
Thermally induced transition from the ordinary phosphorescence to the delayed fluorescence in the two kinds of luminescent Copper(I) complexes is comprehensively investigated by using variable-temperature time-integrated and time-resolved photoluminescence measurements as well as model analysis. Pronounced impact of molecular structure on the exciton transfer from the lowest excited triplet spin states to the singlet spin states with higher energy is firmly demonstrated.
Set of manganese ions activated fluoride phosphors (A2BF6:Mn4+, A=K, Na, B=Si, Ge, Ti): Synthesis below 0 oC and efficient room-temperature photoluminescence - Journal of Materials Chemistry C (RSC Publishing)
Transition-metal-ions activated solid-state phosphors are of particular interest for the development of LED-based white light sources. In addition to their relatively low cost, these luminescent materials show exceptionally high luminescence efficiency, especially at room temperature and above, due to the involvement and promotion of thermal phonons.
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