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Zaohong Ran on Muck Rack

Zaohong Ran

As seen in: BioRxiv
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Articles

FOSL2 regulates gonadotropin-dependent folliculogenesis through feedback amplification of FSH/FSHR signaling

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By Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao
| BioRxiv
Abstract The meticulous orchestration of gonadotropin-dependent folliculogenesis constitutes the cornerstone of female reproductive cyclicity and fertility, with FSH/FSHR signaling recognized as the master regulator. Achieving the necessary amplification of this signaling is essential for successful GTH-dependent folliculogenesis, yet the mechanisms remain inadequately defined.
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FOSL2 Directly Regulates FSHR and CYP11A1 Transcription: An Essential Transcription Factor for Gonadotropin-Dependent Folliculogenesis

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By Hongru Shi, Jianning Liao, Chaoli Chen, Zaohong Ran
| BioRxiv
Abstract Fosl2, a member of the AP-1 family, has been widely studied in the fields of tumorigenesis and immune response, but its role in folliculogenesis remains unclear. In this investigation, we presented comprehensive in vitro and in vivo evidence to precisely define the biological functions of Fosl2 in folliculogenesis.
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