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Ze-qun Yin on Muck Rack

Ze-qun Yin

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Articles

Restoration of cyclin A2 by glabridin reverses pathological cell cycle arrest and drives cardiac repair in HFpEF

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By Meng-Yao Wang, Jie Zhou, Xiao Wen, Chang Yuan, Lu Tang, Hao Wang, Han Xiao, Shuang Zhang, Ru-ru Pan, Sha-sha Chen, Yan-lu Han, Wen-quan Hu, Ya-jun Duan, Ze-qun Yin
| Nature Verified
Abstract Heart failure with preserved ejection fraction (HFpEF) is a pervasive clinical syndrome characterized by complex and elusive pathogenic mechanisms. In this study, we identify aberrant cardiomyocyte cell cycle arrest as a previously unrecognized pathological driver of HFpEF that hinders tissue repair.
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