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Pomegranate Peel Polyphenol Extract Ameliorates Hyperuricemia by Inhibiting Uric Acid Synthesis and Reabsorption
1 Introduction Hyperuricemia (HUA) is a metabolic disorder characterized by elevated serum uric acid (SUA) levels exceeding the normal saturated threshold, a condition arising from purine metabolism dysfunction (Hou et al. 2021; C. Zhang et al. 2020). The clinical diagnostic criteria are defined as SUA levels > 420 μmol/L in men and > 360 μmol/L in women on two separate fasting occasions (Johnson et al. 2026).
Lysine demethylase 1A alleviates Alzheimer disease progression by regulating the leucine carboxyl methyltransferase 1/protein phosphatase 2 catalytic subunit alpha/transcription factor EB pathway via O‐GlcNAcase‐mediated forkhead box transcription factor
AAV adeno-associated virus AD Alzheimer disease FOXA2 forkhead box transcription factor A2 LCMT1 leucine carboxyl methyltransferase 1 LSD1 lysine demethylase 1A (KDM1A) NC negative controls oe overexpression O-GlcNAc O-linked N-acetylglucosamine O-GlcNAcylation O-linked N-acetylglucosamine glycosylation OGA O-GlcNAcase OGT O-GlcNAc transferase qRT-PCR quantitative real-time PCR TFEB transcription factor EB What is already known?
DPG-LSTM: An Enhanced LSTM Framework for Sentiment Analysis in Social Media Text Based on Dependency Parsing and GCN
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