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Zhanying Han on Muck Rack

Zhanying Han

As seen in: MDPI, International Journal of Cardiology
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Articles

Distribution and Genetic Characteristics of Seoul Virus in Different Organs of Rattus norvegicus

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By Yamei Wei, Xiaodong Shi, Yanan Cai, Zhanying Han
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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LncRNA KCNQ1OT1 as a miR-26a-5p sponge regulates ATG12-mediated cardiomyocyte autophagy and aggravates myocardial infarction

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By Yanjun Zhou, Jinbei Li, Yalin Tong, Zhanying Han
| International Journal of Cardiology Verified
Highlights • Elevated KCNQ1OT1 and reduced miR-26a-5p were observed in serum of MI patients and I/R-induced mouse model. • Knockdown of KCNQ1OT1 suppressed H/R-induced cell autophagy and apoptosis. • KCNQ1OT1 acted as a sponge of miR-26a-5p, and ATG12 was a target gene of miR-26a-5p. • KCNQ1OT1/miR-26a-5p/ATG12 axis regulated autophagy and apoptosis. Abstract Background As a dominant cardiovascular disease, myocardial infarction (MI) causes a considerable mortality globally.
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