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Zhongmou Chao

As seen in: Nature, MDPI
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Articles

Tutorial: biomembranes in hybrid living bioelectronics

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By Jeremy Treiber, Zhongmou Chao, Susan L. Daniel, Roisin Owens, Alberto Salleo, Francesca Santoro, Anna-Maria Pappa, Alice Hattar, Jawaher Alhammadi, Darius Hoven, Andreas Offenhaeusser
| Nature Verified
Abstract The integration of biological and artificial systems promises the effective coupling of living cells with electronic devices.
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Recreating the biological steps of viral infection on a cell-free bioelectronic platform to profile viral variants of concern - Nature Communications

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By Zhongmou Chao, Konstantinos Kallitsis, Zixuan Lu, Roisin Owens, Ekaterina Selivanovitch
| Nature Verified
Abstract Viral mutations frequently outpace technologies used to detect harmful variants. Given the continual emergence of SARS-CoV-2 variants, platforms that can identify the presence of a virus and its propensity for infection are needed. Our electronic biomembrane sensing platform recreates distinct SARS-CoV-2 host cell entry pathways and reports the progression of entry as electrical signals.
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A pseudo‐surfactant chemical permeation enhancer to treat otitis media via sustained transtympanic delivery of antibiotics

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By Sophie Liu, Joanna White, Zhongmou Chao
| pericles.pericles-prod.literatumonline.com
Chemical permeation enhancers (CPEs) represent a prevalent and safe strategy to enable non-invasive drug delivery across skin-like biological barriers such as the tympanic membrane (TM). While most existing CPEs interact strongly with the lipid bilayers in the stratum corneum to create defects as diffusion paths, their interactions with the delivery system, such as polymers forming a hydrogel, could compromise gelation, formulation stability, and drug diffusion.
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