Zhongying Han

Abstract To elucidate the mechanism by which acidification influences wellbore stability in deep reservoir formations, this study investigates the rheological and mechanical behaviors of the carbonate rock subjected to high-temperature acid etching.

eLife Assessment This important study combines a comprehensive range of biophysical, kinetic, and thermodynamic techniques, together with high-quality experimental and computational analysis, to carry out a series of well-designed experiments to explore whether glutamine-binding protein binds glutamine via an induced fit or a conformational selection process. The evidence supporting the major conclusion of the work is compelling. The work will be of broad interest to biochemists and biophysicists.

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