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Zhouhui Wu on Muck Rack

Zhouhui Wu

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Articles

M2-polarized RAW 264.7 macrophage-derived exosomal miR-383-5p alleviates chronic periodontitis by targeting ACSL4 to regulate osteogenic and osteoclastogenic differentiation

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By Beibei Li, YUAN ZHANG, Yirong Zhu, Jianying Xiong, Zhouhui Wu
| Nature Verified
Abstract Chronic periodontitis (CP) is characterized by inflammatory alveolar bone destruction. M2 macrophage-derived exosomes (M2-exosomes) may restore bone homeostasis, but the contribution of ACSL4-associated ferroptosis and lipid-peroxidation signaling remains insufficiently defined. This study investigated the function and mechanism of M2-exosomal miR-383-5p in CP.
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