Zhuoxia Li

Introduction Lower extremity arteriosclerosis obliterans (LEASO) is a disease of lower limb hypoperfusion resulting from lipid metabolism disorders and vascular endothelial injury, which trigger inflammatory cell infiltration, lipid deposition, and smooth muscle cell proliferation, leading to the gradual formation of atherosclerotic plaques in the intima of the lower extremity arteries, and ultimately causing arterial stenosis or even occlusion.

Introduction Lower extremity arteriosclerosis obliterans (LEASO) is a disease of lower limb hypoperfusion resulting from lipid metabolism disorders and vascular endothelial injury, which trigger inflammatory cell infiltration, lipid deposition, and smooth muscle cell proliferation, leading to the gradual formation of atherosclerotic plaques in the intima of the lower extremity arteries, and ultimately causing arterial stenosis or even occlusion.