Zin W. Myint
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Sertoli cell tumor in familial adenomatous polyposis: a case report
Abstract Familial adenomatous polyposis is known to progress into colorectal cancer, and extra-intestinal malignancies have also been reported. However, testicular sex cord stromal tumors are very rarely noted in association. In this study, we report the case of a 50-year-old man with genetically confirmed FAP and adenocarcinoma of the colon who was incidentally found to have a testicular lesion.
Real-world incidence of G3-G4 adverse events with enfortumab vedotin in patients with advanced urothelial carcinoma (ARON-2EV study)
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Abstract Enfortumab vedotin (EV) is an antibody–drug conjugate targeting Nectin-4 and is approved for patients with advanced urothelial carcinoma (UC) who have progressed after platinum-based chemotherapy and immune checkpoint inhibitors. While clinical trials have demonstrated manageable safety profiles, real-world toxicity data remain limited.
By Patrizia Giannatempo, Shilpa Gupta, Mimma Rizzo, Karl J.J. Mayrhofer, Renate Pichler, Dora Niedersuess-Beke, Ondrej Fiala, Javier Molina-Cerrillo, Marc Matrana, Luca Galli, Tomas Buchler, Alina Pirshtuk, Jawaher Ansari, Anca Zgura, Ray Manneh Kopp, Giandomenico Roviello, Jindřich Kopecký, Akihiro Yano, Martin Angel, Ravindran Kanesvaran, Zin W. Myint, Yuksel Urun, Francesco Massari, Kannan Sridharan, Matteo Santoni, Randi Kinhel, Alessia Salfi, Kirstin Binz
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Nature
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QOL, Pain Not Changed by 177Lu-PSMA-617 Triplet in mHSPC
The combination of lutetium Lu 177 prostate-specific membrane antigen 617 (177Lu-PSMA-617; Pluvicto) with androgen deprivation therapy (ADT) and an androgen receptor pathway inhibitor (ARPI) produced similar quality-of-life (QOL) outcomes vs ADT/ARPI alone in patients with metastatic hormone-sensitive prostate cancer (mHSPC), according to findings from the phase 3 PSMAddition trial (NCT04720157).1 These findings were preceded by data demonstrating an improvement in radiographic...
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