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Research progress on immune checkpoint inhibitors in intrahepatic cholangiocarcinoma
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a relatively uncommon but lethal neoplasm of the biliary tract. Evolving immunotherapy has important implications for the treatment of ICC. Novel immune checkpoint inhibitors (ICIs) continue to be identified and have demonstrated clinical efficacy in the treatment of ICC, though there are some issues.
Dysregulation of lncRNA OIP5‐AS1 participants in the progression of diabetic retinopathy and affects the proliferation in retinal vascular endothelial cell
INTRODUCTION In recent decades, the prevalence of diabetes mellitus (DM) has exhibited an upward trend, thus classifying it as the third most serious chronic non-communicable disorder that endangers human health on a global scale1. Within China, the number of adults afflicted with DM is increasing annually, a development that is a cause for concern2. Diabetic retinopathy (DR) is a common microvascular complication of DM, constituting the foremost cause of visual impairment globally.
Synergistic toughening effects of elastomer toughener and nucleating agent on mechanical properties and crystallization behaviors of polypropylene
Supporting Information Filename Description pat6578-sup-0001-FigureS1.docxWord 2007 document , 49.3 KB Figure S1. Angular frequency dependence of (a) complex viscosity and (b) storage modulus of neat PP and PP/KN blends at 200°C. REFERENCES 1, . A review of flame retardant polypropylene fibres. Prog Polym Sci. 2003; 28(11): 1517-1538. 2, , , , , .
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