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Results from the BJD survey on readership views towards clinical practice guidelines
RESEARCH LETTER Z.Z.N. Yiu Corresponding Author E-mail address: zenas.yiu@manchester.ac.uk Centre for Dermatology Research, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, Manchester, M13 9PT UK Correspondence Zenas Yiu Email: zenas.yiu@manchester.ac.uk Search for more papers by this author This article has been accepted for publication and undergone full peer review but has not been...
Longitudinal analysis of the effect of water hardness on atopic eczema: evidence for gene-environment interaction
Summary Background Several studies have identified an association between water hardness and atopic eczema (AE ); however, there is a paucity of longitudinal data in early life. Objectives To examine whether water hardness is associated with an increased risk of AE and skin barrier dysfunction in infants and to assess effect modification by filaggrin (FLG ) loss‐of‐function variants.
适用于斑块状银屑病的 risankizumab 与 ustekinumab:严格评读
Summary 银屑病是一种导致鳞片状、红疹的皮肤病,其受累部位从仅小面积(如肘关节和膝关节)到更大面积不等。在英国约2%的人患有银屑病。该疾病有许多治疗方法,包括药膏、片剂和注射剂。注射剂称为生物制剂,免疫系统的这种靶向特异性成分对银屑病非常有效。本文的英国作者旨在评估两项比较两种这类生物制剂 risankizumab 和 ustekinumab 的试验(称为 UltIMMa‐1 和 UltIMMa‐2)的质量。上述试验包括来自...
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