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Zucheng Wang on Muck Rack

Zucheng Wang

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Articles

ArgR regulates the nrf operon to defend against nitrosative and oxidative stress in Aeromonas veronii

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By Xiaoli Jiang, Xiang Ma, Yanqiong Tang, Juanjuan Li, Min Lin, Zhu Liu, Zucheng Wang
| Nature Verified
Abstract Nitrite reductase Nrf, encoded by the nrf operon, plays a central role in bacterial responses to nitrosative and oxidative stress under anaerobic conditions. In this study, we show that the pathogenic strain Aeromonas veronii C4 also expresses nrf and exhibits measurable nitrite reductase activity under aerobic growth conditions. Combined ChIP-seq and RNA-seq analyses identify ArgR as a direct negative regulator of nrf transcription.
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