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Articles

Translational T-box riboswitches bind tRNA by modulating conformational flexibility

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By Sneha Paul, Eduardo Campos-Chavez, Zunwu Zhou, Dulce Alonso
| biorxiv.org
Abstract T-box riboswitches, paradigmatic non-coding RNA elements involved in genetic regulation in most Gram-positive bacteria, are adept at monitoring amino acid metabolism through direct interactions with specific tRNAs. T-box riboswitches assess tRNA aminoacylation status, subsequently regulating the transcription or translation of downstream genes involved in amino acid metabolism.
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