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Zuxiong Zhang on Muck Rack

Zuxiong Zhang

As seen in: Frontiers in Immunology
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Articles

Immunoregulatory mechanisms in parasitic eosinophilic lung disease: the role of IgE immune complexes and NLRC4 inflammasome

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By Yuanchao Cao, Dingyu Rao, Zongbo Peng, Zihao Chen, Qinghui Xia, Defa Huang, Chuan Yao, Chunfa Xie, Yanglin Fu, Zuxiong Zhang
| Frontiers in Immunology
Abstract Parasitic eosinophilic lung disease is characterized by eosinophil infiltration and dysregulated immune responses, posing significant challenges due to its complex immunoregulatory mechanisms which remain incompletely understood. This review explores the emerging role of IgE immune complexes (IgE ICs) in modulating eosinophilic immune responses, proposing a hypothetical signaling axis involving the NLRC4 inflammasome that may influence disease progression.
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