A. Sloan Devlin on Muck Rack

A. Sloan Devlin

As seen in: Nature, Cell Host & Microbe
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Articles

The role of gut microbial metabolites in the T cell lifecycle - Nature Immunology

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By Jun R Huh, A. Sloan Devlin
| Nature
Abstract T cells, a cornerstone of the adaptive immune system, have pivotal roles at the host–microorganism interface. The gut microbiome profoundly influences T cell biology by producing a diverse repertoire of small molecules that are sensed by host cells. These microbial metabolites regulate all aspects of the T cell lifecycle, from cell development to differentiation and activation to exhaustion.
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Alterations in intestinal bile acid transport provide a therapeutic target in patients with post-bariatric hypoglycaemia - Nature Metabolism

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By Rafael Ferraz-Bannitz, Pilar Casanova Querol, Eric G. Sheu, A. Sloan Devlin
| Nature
Abstract While Roux-en-Y gastric bypass is an effective treatment for obesity and type 2 diabetes, up to one-third of patients develop post-bariatric hypoglycaemia (PBH). Individuals with PBH exhibit increased postprandial secretion of the intestinal hormone fibroblast growth factor 19 (FGF19, Fgf15 in mice). However, the underlying mechanisms contributing to PBH remain uncertain.
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A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery

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By David Harris, Andrei Moscalu, Ali Tavakkoli, A. Sloan Devlin
| Cell Host & Microbe
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