Abel Tenaw Tasamma

Löfgren syndrome should be included in the differential diagnosis for a young patient presenting with arthritis, fever, and skin lesions resembling erythema nodosum (EN). 1 Introduction Sarcoidosis, a multi-system granulomatous disease that predominately affects the lungs and skin [1].

1 Introduction Chronic myeloid leukemia (CML) is a clonal myeloproliferative stem cell disorder characterized by the dysregulated production and uncontrolled proliferation of mature and maturing granulocytes, which show relatively normal differentiation. CML is associated with the fusion of the BCR gene on chromosome 22 and the ABL1 gene on chromosome 9, resulting in the BCR::ABL1 fusion gene, which encodes a non-receptor tyrosine kinase that becomes deregulated and constitutively active.