Adam B. Schroer

Main text (Immunity 59, 458–476.e1–e13; February 10, 2026) In the version of the article that was originally published, the legend colors in Figure 2K were inadvertently reversed: CD8 should appear in green and PD1 in red. This has now been corrected in the figure panel and the corresponding figure legend. In Figure 4J, the bottom left panel (Old WT IL-10) was inadvertently populated by the same image as the top right panel (Old control) during the final figure assembly.

Keywords immune aging cognitive decline peripheral immune brain cross-talk hippocampus brain aging rejuvenation parabiosis Introduction Aging is associated with cognitive decline1 and pro-aging systemic interventions promote cognitive dysfunction in young animals.2,3 As such, it is essential to identify peripheral cellular and molecular drivers of age-related cognitive impairments as targets by which to restore cognition in old age.

ArticleOnline nowOpen access 1Department of Genetics, Stanford University, Stanford, CA, USA 2Department of Anatomy, University of California, San Francisco, San Francisco, CA, USA 3Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA 4Stanford Medical Scientist Training Program, Stanford University, Stanford, CA, USA 5Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA 6Wu Tsai Neurosciences...