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Adam Ioannou

As seen in: Wiley Online Library, European Journal of Hospital Pharmacy, heart, Postgraduate Medical Journal, JAMA (The Journal of the American Medical Association), JAMA Cardiology, Dialnet - Universidad de La Rioja, JACC (Journal of the American College of Cardiology), The Journal of Pediatrics, Respiratory Medicine
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Articles

Clinical Phenotype and Prognostic Significance of Frailty in Transthyretin Cardiac Amyloidosis:

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By Carlo Fumagalli, Adam Ioannou, Francesco Cappelli, Mathew S. Maurer
| JACC (Journal of the American College of Cardiology)
References 1. "Impact of earlier diagnosis in cardiac ATTR amyloidosis over the course of 20 years". Circulation . 2022;146:1657-1670. 2. "Sex differences among patients with transthyretin amyloid cardiomyopathy – from diagnosis to prognosis". Eur J Heart Fail . 2022;24:2355-2363. 3. "Early diagnosis and outcome in patients with wild-type transthyretin cardiac amyloidosis". Mayo Clin Proc . 2021;96:2185-2191. 4. "Efficacy and safety of acoramidis in transthyretin amyloid cardiomyopathy". N Engl J Med .
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The Last Decade in Cardiac Amyloidosis: Advances in Understanding Pathophysiology, Diagnosis and Quantification, Prognosis, Treatment Strategies, and Monitoring Response

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By Marianna Fontana, Adam Ioannou, Sarah Cuddy, Sharmila Dorbala
| JACC (Journal of the American College of Cardiology)
Introduction Amyloidosis is a clinical disease process characterized by the deposition of amyloid fibrils within the extracellular space of various organs. Amyloid fibrils are formed when proteins with an unstable tertiary structure misfold into insoluble beta-pleated sheets, resistant to proteolysis, that subsequently aggregate and deposit within the extracellular matrix.
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Kidney Outcomes in Transthyretin Amyloid Cardiomyopathy

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By Adam Ioannou, Muhammad U Rauf, Ana Martinez-Naharro
| JAMA Cardiology
Key Points Question What is the prognostic importance of a decline in kidney function in patients with transthyretin amyloid cardiomyopathy (ATTR-CM)? Findings In this cohort study of 2001 patients, 481 patients (24.0%) experienced a decline in kidney function (defined as a decrease in estimated glomerular filtration rate by more than 20% at 1 year).
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