Skip To Main Content
Adrian Murray Brunt on Muck Rack

Adrian Murray Brunt

As seen in: National Institutes of Health, The Lancet
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Adrian Murray

Contact Adrian Murray, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 10-year efficacy and late normal tissue effects from a multicentre, open-label, non-inferiority, phase 3, randomised controlled trial and 5-year efficacy results from a randomi

|
By Adrian Murray Brunt, Anna Kirby, Mark A Sydenham
| The Lancet Verified
Introduction Radiotherapy after primary surgery in people with early-stage breast cancer reduces locoregional cancer recurrence and breast cancer mortality.1,2 Historically, adjuvant radiotherapy was delivered as 25 fractions of 2 Gy over 5 weeks.
Open in Who Shared Issue with article?

Breast cancer radiation therapy - Authors' reply

|
By Adrian Murray Brunt, Joanne Haviland, Duncan Wheatley, John Yarnold
| The Lancet Verified
Adrian Murray Brunt Joanne S Haviland Duncan A Wheatley John R Yarnold Birgitte Offersen and Jens Overgaard argue that 26 Gy in five fractions is biologically inferior to 40 Gy in 15 fractions on the basis of α/β point estimates; however, therapeutic ratio is better defined clinically. In the FAST-Forward trial, 1 Brunt AM Haviland JS Wheatley DA et al.
Open in Who Shared Issue with article?

Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer

|
By Adrian Murray Brunt, Joanne Haviland, Mark A Sydenham, Rajiv K. Agrawal
| ascopubs.org
Ten-year results of 4 randomized trials totaling > 7,000 patients confirm the safety and efficacy of hypofractionated radiotherapy after primary surgery for early breast cancer.1-4 The UK START-B and Ontario trials established 15- and 16-fraction schedules as new standards of care delivered over 21-22 days.5-7 Sensitivity to fraction size was tested in the START pilot and START-A trials by controlling for treatment time, generating an α/β estimate of 3.5 Gy (95% CI, 1.2 to 5.7) for tumor...
Open in Who Shared Issue with article?
See all 5 articles