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Aida Husain

As seen in: PLOS ONE, Cell Reports
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Articles by Aida Husain

Conserved disordered regions and ubiquitin-binding motifs within HUWE1 contribute to substrate targeting plasticity

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By Xuezhen Ge, Fulin Jiang, Chumo Chen, Aida Husain, Eric Bennett, Caesar A. De La Fuente, Trivikram Rajkhowa, Rathipriya Viswanathan
| Cell Reports Verified
Results HUWE1 has been reported to target a broad range of substrates, including transcription factors, kinases, and other regulatory proteins.32,42 However, our previous work suggested that many HUWE1 substrates are cell type-specific.26 To identify a set of HUWE1 substrates that can be used to interrogate HUWE1 function across different cell and tissue types, we quantified proteome-wide protein abundance changes upon HUWE1 disruption across multiple cell lines.
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Substrate preference of protein kinase B isoforms can vary depending on the cell line

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By Miguel Palma, Samantha Perez, Aida Husain
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Palma MS, Perez SR, Husain A, Bhandari D (2024) Substrate preference of protein kinase B isoforms can vary depending on the cell line. PLoS ONE 19(3): e0298322. https://doi.org/10.1371/journal.pone.0298322 Editor: Yanlin Yu, NCI: National Cancer Institute, UNITED STATES Received: May 10, 2023; Accepted: January 22, 2024; Published: March 19, 2024 Copyright: © 2024 Palma et al.
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