Aiden Maloney-Bertelli

Abstract Photoreceptors initiate vision by converting photons to electrical activity. The onset of the phototransduction cascade is marked by the isomerization of photopigments upon light capture. We revealed that the onset of phototransduction is accompanied by a rapid (<5 ms), nanometer-scale electromechanical deformation in individual human cone photoreceptors.

V. P. Pandiyan, A. M. Bertelli, J. Kuchenbecker, K. C. Boyle, T. Ling, B. H. Park, A. Roorda, D. Palanker, and R. Sabesan, “The optoretinogram reveals the primary steps of phototransduction in the living human eye,” Sci. Adv. 6, eabc1124 (2020). [Crossref] P. Zhang, B. Shibata, G. Peinado, R. J. Zawadzki, P. FitzGerald, and E. N. Pugh, “Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram,” Invest. Ophthalmol. Visual Sci. 61(3), 9 (2020). [Crossref] T. Ling, K. C. Boyle, V.