Ajay Gupta on Muck Rack

Ajay Gupta

As seen in: Wiley Online Library, Frontiers, U.S. News and World Report, Business Standard, Royal Society of Chemistry, EClinicalMedicine, The Lancet, Chemistry World, Chief Executive Magazine, CIOTechOutlook and

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Ajay Gupta’s Biography

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I don't think of myself as hot or cool or anything, just a dork.

How to Reduce Obesity

Articles

Development and Application of Prime Editors for the Induction of Site-Specific, Heritable Edits in Soybean [ Glycine max (L.) Merr.]

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By Nirmal khadka, Ajay Gupta, Hien Thuy Bui
| Wiley Online Library Verified
To the Editor, CRISPR-Cas9-based Prime Editors (PEs) enable precise and programmable DNA modifications without requiring double-strand breaks or donor DNA templates (Anzalone et al. 2019). A PE consists of a nickase Cas9 (nCas9) fused to a reverse transcriptase (RT), guided by a Prime Editing guide RNA (pegRNA) (Figure 1a). This system expands the scope of genome editing with improved precision and minimal off-target effects, making it as a powerful toolkit for crop improvement (Chen and Liu 2023).
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A sham-controlled randomised trial evaluating the safety, acceptability, and efficacy of autonomic neuromodulation using transcutaneous vagal sensory stimulation in uncontrolled hypertensive patients: rationale and study design of the SCRATCH-HTN study

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By Ajay Gupta, David Collier, James Steckelmacher, Jane Field, Mital Patel, George Collett, Annastazia E Learoyd, Alexander V. Gourine, Peter Sever, Olivier Zongo, Everard Mascarenhas, Andrey Gourine
| Frontiers
Abstract Background: Despite the broad availability of antihypertensive drugs, approximately 40% of hypertensive patients fail to achieve the recommended blood pressure (BP) levels and may require alternative treatment(s). At present, renal denervation is the only proven non-pharmacological device-based alternative treatment available, but it is a costly, invasive, hospital-based procedure that is unlikely to be widely available.
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Harnessing the power of iridium AIEgens for NAD(P)H detection in aqueous medium and living cells

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By Ajay Gupta, Jawaharlal Nehru, Aryan Gautam, Smaranika Patra
| Royal Society of Chemistry Verified
Harnessing the power of iridium AIEgens for NAD(P)H detection in aqueous medium and living cells† A rationally designed luminescent probe based on cyclometalated iridium(III) AIEgens was developed for the rapid, sensitive, and specific detection of NAD(P)H in aqueous media. This probe was successfully utilized for bioimaging of NADH within the mitochondria of living cancer cells, highlighting its potential as a valuable tool for investigating NADH-associated cellular processes.
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