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Ajay Nair on Muck Rack

Ajay Nair

Verified
East London, London
As seen in: Sky News, LinkedIn, Medium, HuffPost, Nature, Wiley Online Library, Yahoo Canada, Yahoo News UK, Daily Express, The Philadelphia Inquirer, Yahoo and
Multi-platform journalist. Making digital videos @SkyNews. Past lives: sub-editor 📱, newsreader 📻, reporter 📰, producer 📺… MC/beatmaker 🎤… ajay.nair@sky.uk

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Articles

FXR–YAP signalling maintains biliary epithelial cell identity and preserves liver homeostasis

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By Zhaoshuo Wang, Sladjana Zagorac, Maria Dominguez, Jasminka Boskovic, Ajay Nair Verified, Andrea Macías-Camero, Alma Villaseñor, Robert Schwabe, Nabil Djouder, Paula Sánchez-Sánchez
| Nature Verified
Abstract Bile acids (BAs) flow through ducts lined by biliary epithelial cells (BECs), which preserve ductal integrity and liver homeostasis. Failure of this barrier causes BA accumulation in the liver parenchyma, and ultimately fibrosis. Here we show that BECs safeguard biliary barrier integrity and restrain BA-induced fibrogenesis through a cell-intrinsic mechanism involving farnesoid-X-receptor (FXR)–YAP signalling.
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Single-cell transcriptomics reveals FXR1 as an actionable target for siRNA therapy in ovarian cancer

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By Jasmine George, Xiaolong Ma, Ishaque Pulikkal Kadamberi, Ajay Nair Verified, Sonam Mittal, Sudhir Kumar, Mona Singh, Anjali Geethadevi, Meenakshi Pradeep, Anupama Nair, Shirng-Wern Tsaih, Julie M. Jorns, Subramaniam Malarkannan, Felix Dietlein, Chien-Wei Lin, Sunila Pradeep, Pradeep Chaluvally-Raghavan, Elaheh Hashemi
| Nature Verified
Abstract Ovarian cancer is one of the leading causes of cancer-related mortality among women and remains exceptionally difficult to manage and treat effectively in the clinic. Fragile X-related protein 1 (FXR1) is highly amplified and overexpressed in ovarian and several other cancers. FXR1 is a key regulator of the translation of multiple oncogenes and therefore represents a vulnerable target for cancer therapy.
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Broccoli Production Resource Highlights Relevant Research for Midwest Growers

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By Ajay Nair Verified, Alaina Friesleben
| iastate.edu
AMES, Iowa – Home gardeners and commercial broccoli growers preparing for spring planting are encouraged to review practical insights from a new Iowa State University Extension and Outreach resource. “Broccoli Production in the Midwest” is available for download at no cost from the ISU Extension Store.
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