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Keywords diffuse midline glioma DMG glioma neuron OPC oligodendrogenesis oligodendrocyte neuronal activity neuron-glioma LDT laterodorsal tegmentum nucleus PPN pedunculopontine nucleus cholinergic neuron Introduction The activity of the nervous system has emerged as a crucial driver of cancers (for reviews, please see Monje et al.,1 Mancusi and Monje,2 and Winkler et al.3), and powerfully drives the initiation,4,5 and growth6,7,8,9,10 of primary brain cancers called gliomas.
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