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Alexandre Toulmay on Muck Rack

Alexandre Toulmay

East Coast United States
As seen in: Nature, BioRxiv, Cell Press
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Articles

The Vps13-like protein BLTP2 regulates phosphatidylethanolamine levels to maintain plasma membrane fluidity and breast cancer aggressiveness - Nature Cell Biology

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By Stephan Daetwyler, Alexandre Toulmay
| Nature Verified
Abstract Lipid transport proteins (LTPs) facilitate non-vesicular lipid exchange between cellular compartments and have critical roles in lipid homeostasis. A recently identified family of bridge-like LTPs (BLTPs) is thought to form lipid-transporting conduits between organelles. One of these, BLTP2, is conserved across species but its function is not known. Here we show that BLTP2 regulates plasma membrane (PM) fluidity by increasing phosphatidylethanolamine (PE) levels in the PM.
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Pln1 Mediates Lipid Droplet-Vacuole Tethering During Microlipophagy Saccharomyces cerevisiae

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By Alexandre Toulmay, Jayaprakash Monala Rao, Brayden Folger, Joshua Reus
| BioRxiv
Abstract Lipid droplets (LDs) are dynamic organelles that undergo growth or degradation depending on the metabolic state of the cell. One form of LD degradation is autophagy-mediated, referred to as lipophagy. Here, we demonstrate that Pln1, a perilipin located on the surface of LDs in Saccharomyces cerevisiae, previously known for its role in LD biogenesis, is essential for lipophagy.
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Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER

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By Kidney Diseases, Alexandre Toulmay, Jerry Yang
| rupress.org
Skip Nav Destination Report| January 11 2022 You do not currently have access to this content. Sign in Client Account You could not be signed in. Please check your email address / username and password and try again. Email address / Username ? Password
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