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Alexias Safi on Muck Rack

Alexias Safi

As seen in: Nature
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Articles

High-throughput characterization of transcription factors that modulate UV damage formation and repair at single-nucleotide resolution

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By Hana Wasserman, Kaitlynne A. Bohm, Mingrui Duan, Harshit Sahay, Alexias Safi, Gregory Crawford, Peng Mao, John J. Wyrick, Miles A. Pufall, Raluca Gordân
| Nature Verified
Abstract Genomic studies revealed elevated DNA damage and mutation rates at transcription factor (TF) binding sites in UV-linked cancers. While TFs can promote UV-induced mutagenesis by altering both damage formation and repair, these mechanisms have not been systematically characterized across TFs at high resolution.
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By Christopher M. Vockley, Ian McDowell, William H. Majoros, Lingyun Song, Gregory Crawford, Anthony M. D’Ippolito, Alexias Safi, Timothy E. Reddy
| secure.jbs.elsevierhealth.com
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